SYNTHESIS OF INDOLE BEARING HETEROCYCLES AND THEIR BIOLOGICAL EVALUATION Dr. PRABHAKER W. CHAVAN Year of Publish -2016 Month - May ISBN : - 978-1-365-21521-6 Book Publication Online or offline 5 copies.         SCIENCE Download : - ****

Back in the early 1970s, I think it is fair to say that heterocyclic chemistry was still considered to be a special field of particular interest to natural product/synthetic compounds and medicinal chemistry, probably meriting special treatment in a specialized journal, but of peripheral interest to the large majority of mainstream organic chemists. How this situation has changed! Heterocycles are now thoroughly integrated into the warp and woof of almost all of organic and medicinal chemistry. The varied uses of heterocycles - as structural motifs for new materials, as protecting groups, as unique solvents and reagents, as latent functionalities in organic synthesis, as chemical entities that can be modified and substituted, but then destroyed to create new, non-heterocyclic or heterocyclic products -constitute an integral part of modern synthetic methodology. Heterocyclic compounds far outnumber aliphatic and carbocyclic compounds, and it has been estimated that some 85-90% of all publications today in organic chemistry utilize or are concerned in one way or another with heterocycles. The broad area of natural products - alkaloids, DNA, vitamins, hormones, sugars, antibiotics, drugs, herbicides, insecticides, pesticides, dyes - is dominated by heterocycles.